The purpose of this online manual is to assist the trainers of Media and Information Literacy (MIL) in teaching subjects related to this topic, as well as in training other potential future trainers in this aspect. This manual is intended as a contribution to trainers of MIL to prepare their educational program, in as easy and interesting way as possible. The manual might be useful to a broad range of actors, such as NGO representatives, teachers involved in MIL, journalists, and other persons interested in education of various target groups. The manual is built in several modules, with the respective exercises and additional materials that can be used for illustrations of the basic concepts of MIL. The handbook is prepared in the framework of the regional project “Media for Citizens – Citizens for Media” – project of seven CSOs for development of media in the Western Balkans (Media Center Sarajevo Foundation, Albanian Media Institute, Macedonian Media Institute, Media Institute of Montenegro, Novi sad School of Journalism, Ljubljana Peace Institute and Media Professionalism Network (SEENPM), aimed at strengthening the capacity of CSOs to promote initiatives related to MIL. The project is funded by the European Union.